Mirco Dindo Selected Research

Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)

1/2022	Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1.
4/2021	Dimerization Drives Proper Folding of Human Alanine:Glyoxylate Aminotransferase But Is Dispensable for Peroxisomal Targeting.
9/2020	The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization.
12/2019	Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: implications for Primary Hyperoxaluria type 1.
1/2018	Correlation between the molecular effects of mutations at the dimer interface of alanine-glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6.
1/2018	Folding Defects Leading to Primary Hyperoxaluria.
1/2016	Natural and Unnatural Compounds Rescue Folding Defects of Human Alanine: Glyoxylate Aminotransferase Leading to Primary Hyperoxaluria Type I.
10/2015	The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I.

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Mirco Dindo Research Topics

Disease

11	Primary Hyperoxaluria (Oxaluria, Primary) 01/2022 - 10/2015
4	Rare Diseases (Rare Disease) 09/2020 - 10/2015
2	Kidney Calculi (Kidney Stone) 01/2022 - 09/2020
2	Primary hyperoxaluria type 1 01/2022 - 12/2019
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2020 - 11/2017
2	Hyperoxaluria (Oxaluria) 02/2019 - 01/2019
2	Aromatic amino acid decarboxylase deficiency 10/2014 - 04/2013
1	Kidney Diseases (Kidney Disease) 01/2022
1	Lactose Intolerance (Intolerance, Lactose) 10/2020
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2019
1	Proteostasis Deficiencies 01/2018

Drug/Important Bio-Agent (IBA)

8	Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)IBA 01/2022 - 10/2015
5	glyoxylic acid (glyoxylate)IBA 01/2022 - 01/2018
5	EnzymesIBA 01/2022 - 01/2018
4	OxalatesIBA 01/2022 - 01/2019
4	Calcium OxalateIBA 12/2019 - 11/2017
3	Proteins (Proteins, Gene)FDA Link 04/2021 - 10/2015
2	PyridoxalIBA 04/2021 - 01/2020
1	LigandsIBA 01/2022
1	LectinsIBA 10/2020
1	CarbohydratesIBA 10/2020
1	Lactose FDA LinkGeneric 10/2020
1	Dopamine (Intropin)FDA LinkGeneric 01/2020
1	Aromatic-L-Amino-Acid DecarboxylasesIBA 01/2020
1	Serotonin (5 Hydroxytryptamine)IBA 01/2020
1	Biological ProductsIBA 12/2019
1	Cycloserine (Seromycin)FDA Link 12/2019
1	Hydroxypyruvate ReductaseIBA 01/2018
1	4-hydroxy-2-oxoglutarate aldolaseIBA 01/2018
1	glyoxylate reductaseIBA 01/2018
1	Vitamin B 6IBA 01/2018
1	AcidsIBA 10/2015
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 04/2013

Therapy/Procedure

1	Therapeutics 10/2014